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Department of Hemostasis and Thrombosis

  1. Screening coagulation assays ( PT, APTT, TT, Factor XIII ).
  2. Coagulation factor assays - Factor II, V, VII, VIII, IX, X, XI, XII, Fibrinogen.
  3. Platelet Function Assays.
  4. Platelet receptor studies by flow cytometry.
  5. VWF antigen estimation.
  6. D Dimer assays.
  7. Platelet antibody quantification by flow cytometry.
  8. Carrier detection in haemophilia by DNA analysis.
  9. First trimester CVS analysis for diagnosis of haemophilia A and B, von Willebrand disease, factor VII and X deficiencies.
  10. Second trimester diagnosis for haemophilia A, B, von Willebrand disease and other rare coagulation factor deficiencies.
  11. Human platelet antigen genotyping for suspected cases of NAITP.
  12. Protein C, protein S , antithrombin III and factor V Leiden mutation.

 New techniques developed

1.       A mismatched priming technique for the detection of common G10430A mutation in hemophilia B patients

2.       A novel ELISA for the diagnosis of Glanzmanns thrombasthenia

3.       A semiquantitative assay for factor XIII

4.       A clot based assay for microparticles

5.       A specific and sensitive assay for factor VIII inhibitors