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Important Announcement

Clinical & Experimental Immunology

About

This Department was established in 1985 which was named earlier as Department of Autoimmune disorders. Around 4000 cases are referred every year of suspected autoimmune disorders. They are screened for autoantibody profile such as anti-nuclear antibodies (ANA), dsDNA autoanitbodies, anti-Neutrophil cytoplasmic antibodies (ANCA). Various other assays such as ELISA, line BLOT assays and nephelometer is used for detection of autoantibodies and associated immune parameters. After the treatment, these patients are followed up at regular intervals for monitoring disease activates over a period of time.

Research projects of this department are mainly focused on immunobiology, immune regulation and immunogenetics of various autoimmune and infectious diseases. This department has recently completed a project on understanding immunoregulatory mechanisms of catalytic antibodies under ICMR-INSERM International Associated Laboratories (IAL) program. Department will also focus on cellular immunological aspects to understand pathophysiology of autoimmune and infectious diseases in future.

Department Staff

Sr. No. Name Designation Email ID
1 Dr. Manisha Madkaikar Scientist G madkaikarmanisha@yahoo.co.in
2 Dr. Vandana Pradhan Scientist C pradhanv69@rediffmail.com
3 Dr. Seema Korgoankar Sr.Tech Officer (3) seema_k27@yahoo.co.in
4 Ms. Manisha Patwardhan Sr.Tech Officer (2) manishapatwardhan@gmail.com
5 Mr. Milind P. Dolas Sr. Tech Officer (2)
6 Mr. Raghunath J. Bali Lab Assistant
7 Mr. Kishor Waghela Lab Assistant
8 Mr.Dilip Bali Lab Assistant

Projects

Ongoing projects

  • Defects in the Fibrinolytic pathway as a cause of bleeding disorder in Indian patients: ICMR Extramural SRF project.
  • Disorders of Fibrinolysis as a cause of Thrombophilia in Indian patients with Deep Vein Thrombosis (DVT): NIIH Intramural Project.
  • Clinical spectrum and molecular basis of thrombotic microangiopathies: NIIH Intramural Project.
  • Genomic and functional characterization of unclassified qualitative and quantitative inherited Platelet disorders.
  • Modulation of the function of activated protein C (APC) to improve the clinical phenotype of haemophilia A.
  • Phenotypic and genotypic characterization of Antithrombin (AT) deficiency in Indian patients with thrombosis.
  • Assessment of diagnostic tests for monitoring bypassing agent therapy in Hemophilia patients with inhibitors.