Important Announcement Tender for Technical and Lab Equipment

Department of Hemostasis and Thrombosis


Name - Dr. Bipin P. Kulkarni

Degree - Post Doctoral Fellowship

Designation - Scientist C

Email - bipinpkulkarni@yahoo.co.in

Degree University Subject Year
Post Doctoral Fellowship Emory University, USA Human Genetics 2007 - 2008
Ph.D. Mumbai Applied Biology 2004
M.Sc. Mumbai Life- Sciences- Biotechnology Specialization 1998
B.Sc. Mumbai Life- Sciences 1996
  • Obtained Award for the poster entitled "A Covalent Reverse Dot Blot (CRDB) hybridization assay for quick detection of arginine hot- spot mutations in von Willebrand Disease", at the 54th Annual Conference of Indian Society of Haematology & Blood Transfusion (ISHBT), 7th- 10th November 2013, Mumbai.
  • The Project "Application of microarray genomic selection (MGS) in DNA diagnostics" received the first ACMG Foundation/Signature Genomics Travel Award at the American College of Medical Genetics conference at Phoenix, AZ, U.S.A. on 14th March 2008.
  • Recipient of Dr.J.C.Patel Best Paper award for the paper entitled "Frequency distribution of Human Platelet Antigens (HPA) in the Indian population and its association with Neonatal Alloimmune Thrombocytopenic Purpura (NAITP)", at the 28th annual conference and CME of Mumbai Hematology Group, Mumbai, March 26-28, 2004.
  • Obtained Best Paper Award for the paper entitled "Study of Human Platelet-Specific Antigen (HPA-1) in Indian Population and detection of cases of Neonatal Alloimmune Thrombocytopenic Purpura (NAITP)", at the Silver Jubilee Conference of ISBTI, Tirupati, 10-12 November 2000.
  • Obtained Best Poster Award for the poster entitled " HPA-1 Polymorphism in the Indian Population- A Preliminary Study ", at the 40th Indian Society of Haematology & Transfusion Medicine (ISHTM), Pune, December 9-12, 1999.
  • Obtained the Lady Tata memorial Junior Research Fellowship during the year June 1999 to June 2000 and extended further to June 2001, awarded for Ph.D. thesis work.
  • Honoured by Ramnarain Ruia College in November 1996 for obtaining the Best- exhibit award (Industrial Fermentation) in its Diamond Jubilee Science Exhibition.
Research Teacher University Subject
Ph.D. Guide Mumbai University Applied Biology
  • Spectrum of mutations in Indian patients with fibrinogen disorders and its application in genetic diagnosis of the affected families.Mukaddam, Alfia; Kulkarni, Bipin; Jadli, Anshul; ghosh, kanjaksha; Shetty, Shrimati. Haemophilia (Accepted for publication).
  • Sense, missense, and nonsense: a novel mechanism of premature termination codon (PTC) mutation in a severe von Willebrand disease (VWD) patient. Kasatkar P, Kulkarni B, Ghosh K, Shetty S. Ann Hematol. 2015 Apr 15. PMID: 25869031.
  • Molecular Pathology of Rare Bleeding Disorders (RBDs) in India: A Systematic Review. Kulkarni BP, Nair SB, Vijapurkar M, Mota L, Shanbhag S, Ali S, Shetty SD, Ghosh K. PLoS One. 2014 Oct 2;9(9):e108683.doi: 10.1371/journal.pone.0108683. eCollection 2014. PMID: 25275492.
  • Spectrum of mutations in Indian patients with fibrinogen disorders and its application in genetic diagnosis of the affected families. Mukaddam, Alfia; Kulkarni, Bipin; Jadli, Anshul; ghosh, kanjaksha; Shetty, Shrimati. Haemophilia (Accepted for publication).
  • Sense, missense, and nonsense: a novel mechanism of premature termination codon (PTC) mutation in a severe von Willebrand disease (VWD) patient. Kasatkar P, Kulkarni B, Ghosh K, Shetty S. Ann Hematol. 2015 Apr 15. PMID: 25869031.
  • Molecular Pathology of Rare Bleeding Disorders (RBDs) in India: A Systematic Review. Kulkarni BP, Nair SB, Vijapurkar M, Mota L, Shanbhag S, Ali S, Shetty SD, Ghosh K. PLoS One. 2014 Oct 2;9(9):e108683.doi: 10.1371/journal.pone.0108683. eCollection 2014. PMID: 25275492.
  • Factor V Leiden mutation modulates the bleeding phenotype in warfarin sensitive patients. Gaikwad T, Ghosh K, Kulkarni B, Shetty S. Thromb Res. 2014 May;133(5):955-6. doi: 10.1016/j.thromres.2014.02.022. Epub 2014 Feb 28. No abstract available. PMID: 24630642.
  • Rare coagulation factor deficiencies: a countrywide screening data from India. Shetty S, Shelar T, Mirgal D, Nawadkar V, Pinto P, Shabhag S, Mukaddam A, Kulkarni B, Ghosh K. Haemophilia. 2014 Jul;20(4):575-81. doi: 0.1111/hae.12368. Epub 2014 Feb 28. PMID: 24581247.
  • Influence of CYP2C9 and VKORC1 gene polymorphisms on warfarin dosage, over anticoagulation and other adverse outcomes in Indian population. Gaikwad T, Ghosh K, Kulkarni B, Kulkarni V, Ross C, Shetty S. Eur J Pharmacol. 2013 Jun 15;710(1-3):80-4 PMID: 23602689.
  • Non conventional mutations associated with myeloproliferative disorders are absent in splanchnic venous thrombosis cases. Jadli A, Kulkarni B, Ghosh K, Shetty S. Liver Int. 2012 Jul 23. doi: 10.1111/j.1478-3231.2012.02851.x. [Epub ahead of print] No abstract available. PMID: 22816981.
  • Hemostasis, Thrombosis, Platelet biology, Molecular Biology.
  • Blood Hemostasis involves the coagulation cascade, which is comprised of coagulation plasma proteins (zymogens) and platelets; the natural anti- coagulants that slow down the clot formation; and the fibrinolytic cascade, which is responsible for degradation of the fibrin clot. These cascades function in perfect balance in physiological conditions. However, loss or gain of function or their altered interactions may lead to manifestations of either prothrombotic or bleeding tendencies. Knowing the pathology behind these conditions not only might be of use in designing personalized treatment options by the treating clinicians, but also corrective measures be designed to rectify the tilted balance of harmony of these cascades by adapting appropriate molecular strategies.