NIIH | On-Going Projects List

Sr. No.	Title
1	CRISPR mediated genetic correction of Sickle cell disease twoards clinical trials in a small patient cohort PI: Dr. Manisha Madkaikar/ Dr. Umair Bargir
2	Use of multi-omic approaches to understand autoinflammatory disorders(AID) and identify targets for precision medicine PI: Dr. Manisha Madkaikar
3	Development and Validation of Artificial Intelligence tool for Screening / Detection of pulmonary TB and other lung diseases using Chest X-Ray. PI: Dr. Reetika Yadav
4	Study on Factors Influencing Implementation of Iron and Folic Acid Supplementation in Pregnant Women under Anaemia Mukt Bharat Program PI: Dr. Amrutha Jose
5	National Registry for Rare and other Inherited disorders (NRROID) PI: Dr. Rucha Patil
6	Cytokine and autoantibody cluster interactions in systemic lupus erythematosus(sle) PI: Dr. Vandana Pradhan
7	To study spectrum of Primary Immunodeficiency Diseases (PID) in North East India & establishment of diagnostic facilities for PID PI: Dr. Manisha Madkaikar / Dr. Maya Gupta
8	Role of newer Biomakers in prediction of reccurence of unprovoked deep venous thombrosis PI: Dr. Bipin Kulkarni
9	Understanding the impact of variants in transcriptional regulators of y-globin gene in Sickle cell disease PI: Dr. Naveen Khargekar
10	Development of nanoparticle-based lateral flow-immunoassay for semi-quantitative estimation of human IGg PI: Dr. Umair Bargir
11	ICMRs National hospital based registry on venous Thombro - Embolic Disorders PI: Dr. Bipin Kulkarni
12	Community based surveillance for adverse events following immunization with BCG vaccine and evaluation for underlying inborn errors of immunity PI: Dr. Reetika Yadav
13	Evaluation of Implementation of Anemia Mukt Bharat (Intensified - National Iron Plus Initiative) in School Children PI: Dr. Naveen Khargekar
14	Study of genome wide expression profiling of long non-coding RNAs (lncRNAs) and mRNA association with myelodysplastic syndromes pathogenesis PI: Dr. Babu Rao Vundinti
15	Understanding immune defects in pediatric non-cystic bronchiectasis and recurrent pneumonia cases: A multicentric study PI: Dr. Umair Bargir
16	Project Staff for Model Rural Health Research Unit (MRHRU) Project PI: Dr. Naveen Khargekar
17	Non-invasive prenatal testing (NIPT) for hemoglobinopathies by a targeted next-generation sequencing assay PI: Dr. Prabhakar Kedar
18	Study for validation of the FibriTimer Zeta-1 semi-automated coagulation analyzer (1 channel) for Health Technology Assessment (HTA) PI: Dr. Rucha Patil
19	Randomized controlled trial of immunosuppressive therapy (ATG+CSA) with eltrombopag and ATG+CSA with romiplostim in aplastic anemia: correlation of therapy response with transcriptomic profiling PI: Dr. Babu Rao Vundinti
20	An in-house point of care (poc) test using lateral flow immunoassay with gold nanoparticle for detection of factor viii inhibitors in haemophilia a patients PI: Dr. Rucha Patil
21	Exploring molecular stratification of systemic lupus erythematosus (SLE) for possible targeted treatment strategies PI: Dr. Vandana Pradhan
22	Assessment of Emicizumab (low dose) in hemophilia patients PI: Dr. Rucha Patil
23	Non-inferiority randomized trial to assess efficacy of 10 mg vs 20 mg hydroxyurea/kg/day in sickle cell disease patients (tribal and non-tribal areas in India) PI: Dr. Naveen Khargekar
24	Developing Hepatitis B core-related antigen (HBcrAg) lateral flow immunoassay (LFIA) platform using carbon quantum dot-based detection PI: Dr. Anindita Banerjee
25	Implementation Research for optimizing the comprehensive Sickle Cell Anemia (SCA) care services under the National SCA Elimanation Mission PI: Dr. Sayali Tiwari
26	Spectrum of respiratory viral infections in hospital admitted sickle cell disease patients PI: Dr. Swapnil Chandekar
27	Investigating the roles of plasma membrane calcium ATPase (PMCA) and Piezo1 in sickle cell disease: implications for pathophysiology and therapeutics PI: Dr. Prashant Warang
28	Unravelling the immune response profile to pneumococcal vaccine in sickle cell disease: a study from Central India PI: Dr. Kalpita Gawit
29	A clinical audit and cause of death study in patients with sickle cell disease (SCD) hospitalized in government hospitals in two districts of Central India PI: Dr. Sayali Tiwari
30	A non-inferiority randomized trial to assess the efficacy of 10 mg hydroxyurea/kg/day versus 20 mg hydroxyurea/kg/day in treatment of sickle cell disease patients in tribal and non-tribal areas in India PI: Dr. Manisha Madkaikar/ Dr. Kalpita Gawit
31	Evaluation of Efficacy and safety of lower dose Emicizumab (1mg every two weeks) with and without loading dose in hemophilia A PI: Dr. Rucha Patil
32	Optimizing Flow-Fish for Telomere Length Measurement and In-House Kit Development PI: Dr. Manisha Madkaikar/ Dr. Maya Gupta
33	EQAS National AIDS Control Organization PI: Dr. Anindita Banerjee

On Going Projects

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