ICMR-NIIH

आई सी एम आर - राष्ट्रीय प्रतिरक्षा रुधिर विज्ञान संस्थान

ICMR-National Institute of Immunohaematology

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Completed Projects
1 Establishment of Prenatal Diagnosis of Thalassemia Syndromes and Sickle Cell Disorders in Madhya Pradesh and Assam
2 Newborn Screening and Molecular Characterzation for Red Cell Enzyme Defects and Hemoglobinopathes in Tripura.
3 Role of Telomere Length and Telomerase activity in clinical outcome of Patients with Thalassemia.
4 Assessing the role of microRNAs in clinical severity of Thalassemia Patients, and in hydroxyurea mediated HbF induction.
5 Role of Erythroid Kruppel-like Factor ( EKLF or KLF1) in hemoglobinopathies.
6 Diagnosis & Molecular Characterization of Hemoglobinopaties
7 Quality Assurance Programme for Molecular and Prenatal Diagnosis of Haemoglobinopathies
8 Prevalence of Hemoglobinopathies in Indigenous tribes of Meghalaya with genetic analysis and study on the role of genetic modifiers
9 Collaborative Effort to Understanding & Characterization of Novel Molecular Changes in Fanconi Anemia (FA).
10 "Molecular Study of Telomerase RANA Component (TERC) Gene, Telomerasereverse transcriptase (TERT) and dyskeratosis conginita (DKC1) gene in idiopathis a plastic anemia"
11 Susceptibility to BCR/ABL Mutations in Vitro and Ex-vivo Studies
12 Molecular Genetics Immunological & Functional Study of the Multidrug Resistance Patients with Leukemias.
13 Study of Single Nucleotide Polymorphisms (SNPs) of multiple candidate genes (ABCB1, ABCG2, CYP3A4, CYP3A5, S;CO1B3,AGP1,SLC22A1) in imatinib resistance chronic myeloid leukemia.
14 Study of Genotypes, Phenotypes and search for new genes in patients of Fanconi anemia with no mutations in known genes
15 Defects in the Fibrinolytic pathway as cause of bleeding disorder in Indian Patients.
16 "Role of NK Cells in immunopathogenesis of Dengue virus infection"
17 "EPITOPE Specificity of factor VIII Inhabitors Correlation with mutations, nature of inhibitor and clinical significance"
18 A rapid nanoparticle-based lateral flow immunoassay for the detection of von Willebrand factor and alloantibodies to von Willebrand factor and Procoagulant Factor FVIII from Human plasma samples.
19 Role of circulating Procoagulant microparticles in women with pregnancy loss both recurrent miscarriages and unexplained fetal loss
20 Genetic Polymorphisms in Bilirubin Metabolism Genes and their association with Unconjugated Hyperbilirubinemia among adults.
21 Folate Metabolism Pathway Gene Polymorphisms among Symptomatic and Asymptomatic Malaria Patients from North East Inida.Part-I
22 Funtional Variations in Coagulation Factor V Gene as a Cause of Idiopathic Venous Thrombosis
23 JAK2 V167F Mutations in patients with Portal Mesenteric Venous Thrombosis in Budd Chari Syndrome and Other Deep Venous Thrombosis Groups.
24 A rapid/novel nanoparticle-based lateral flow Immuno Assay ( LFIA) for the detection of von willebrand factor and alloantibodies to Von Willebrand factor and Procoagulant Factor FVIII from Human plasma samples.
25 Folate Metabolism Pathway Gene Poumorphisms among Symptomatic and Asymptomatic Malaria Patients from North East Inida. - II
26 Phenotypic and Genotypic Characterization of Protein C deficiency cases and their association with Clinical manifestation.
27 Microparticles versus Thrombin Generation Assays as Predictive Tests for Monitoring Bypassing Agents in Hemophilia Patients with Inhibitors
28 Molecular Basis of Hyperbilirubinemia among The neonates in India.
29 Micro Mapping of G6PD deficiency Among the Tribals of India and its Importance for Antimalarial Therpy
30 Newborn Screening for Sickle Cell Disease and providing comprehensive care to understand the natural history of Sickle Cell Disease in Tribals.
31 Socio Ecological Imapact & Tribal Health: A study on Epidemiological diversity of Thalassemia mutations among Tribes in India and Impact of Socio-Ecological infuluences.
32 Understanding the Unexplained Hyperbilirubinemia in Hemogolobinopathies.
33 Establishment of prenalal Diagnosis of Hemoglobin E disorders and β Thalassemia Syndromes in Tripura
34 Understanding the role of Neutrophil Extracellular trap (NET) formation in pathophysiology of Chronic Granulomatous disease (CGD) patients.
35 Study the role of T Cell Receptor Excision Circle ( TREC) assay in diagnosis of various combined immunodeficiency disorders.
36 Delayed Vitamin K Deficiency Genetic Profile of Factors in Vitamin K Cycle and Gama Carboxylation System.
37 India-Japan Collaborative research aspiring for Conquering Sickle Cell Disease by Dlucidating the Developmental Mechanisms.
38 Harnessing pleuripotent stem cells (iPSCs) technology for understanding the pathophysiology and management of human primary Immunodeficiency Disorders
39 Understanding of Molecular Pathology of Chronic Granulomatous Disease (CGD).
40 India-Japan Collaborative research aspiring for prevention and diagnosis of erythrocyte associated diseases.
41 Understanding Molecular Pathology of Hemophagocytic Lymphoshistiocytosis (HLH) in India.
42 Explicating the role of programmed Death-1 (PD-1) expressing CD8T Cells in Hemophagocytic Lymphohistiocytosis (HLH).
43 Molecualr Characterization of undiagnosed cases of congenital hemolytic anemia using a multigene next generation sequencing panel
44 Collaborative effort to study Pathophysiology and molecular characterisation of congenital anemia in India.
45 Red Cell membrance molecular pathology in hereditary spherocytosis (HS) in India.
46 An in-house lateral flow immunoassa (LFIA) based point of care (POC) test using gold nanoparticle labeled antigens/ antibodies for detecton of COVID-19 iGg/IgM antibodies
47 Comparative Study of Red Cell antigen profile among Malaria infected patients and normal population from Assam and Mumbai.
48 Indentification and Molecular Characterization of D Variants among apparently RhD negative individuals.
49 Comparative Analysis of Red Blood Cell Antigen Typing among the indigenous populations of Meghalaya and native population of Mumbai
50 Establishment of Basic Red Cell Serology technique in Blood banks of the North East Region of India
51 Molecular Study of RH Gene Variants in Indians
52 "Systemic Lupus Erythematosus (SLE) - An Investigation into diagnostics and disease pathogenesis"
53 The Mannose-Binding Lectin Gene Polymorphism in Systemic Lupus Erythematosus (SLE)(MBL).

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